Sure, here are 20 potential topics that could be covered in a course to become a YouTube star and earn money:

1. Introduction to YouTube and its monetization opportunities.
2. Understanding different types of YouTube content, including vlogs, tutorials, and reviews.
3. Identifying your niche and target audience on YouTube.
4. Developing a YouTube content strategy.
5. Creating engaging video content, including filming, editing, and uploading.
6. Using YouTube SEO techniques to optimize video content for search.
7. Building a YouTube channel brand and creating a visual identity.
8. Engaging with your audience through comments, live streaming, and community features.
9. Understanding the legal aspects of YouTube content creation and copyright.
10. Developing partnerships and collaborations with other YouTube creators.
11. Using YouTube Analytics to measure the success of your channel.
12. Understanding the different monetization opportunities on YouTube, including AdSense, sponsorships, and merchandise sales.
13. Building a YouTube subscriber base and driving traffic to your channel.
14. Creating engaging thumbnails and titles to attract views.
15. Developing a YouTube marketing plan and using social media to promote your content.
16. Using YouTube to build a personal brand and establish yourself as an authority in your niche.
17. Best practices for YouTube channel growth and optimization.
18. Tips for increasing engagement and retention on your YouTube channel.
19. Understanding YouTube algorithm updates and how they affect your channel.
20. Staying up-to-date with emerging trends and best practices in YouTube content creation and marketing.

These are just a few potential topics that could be covered in a course to become a YouTube star and earn money. The actual curriculum and content may vary based on the instructor, institution, and student needs.